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September 7, 2008Nucleic Acids Research259 citationsOpen Access

ExplorEnz: the primary source of the IUBMB enzyme list

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AMAndrew G. McDonaldSBSimone Peart BoyceKTKeith F. Tipton

Key Points

  • To introduce ExplorEnz, the primary relational database system designed for curating and disseminating the official International Union of Biochemistry and Molecular Biology (IUBMB) Enzyme Nomenclature list.
  • Constructed a relational database infrastructure using MySQL to store and manage enzyme nomenclature records.
  • Developed an online interface offering basic lookup and advanced Boolean query functionalities, along with SQL and XML export tools.
  • Implemented a web-based curatorial workflow that manages peer review, public feedback, and community submissions for new or revised enzyme entries.
  • Established an open-access web portal at enzyme-database.org for querying and downloading full enzyme classification datasets.
  • Streamlined the enzyme classification lifecycle by integrating submission, internal review, and public evaluation into a unified digital pipeline.

Abstract

ExplorEnz is the MySQL database that is used for the curation and dissemination of the International Union of Biochemistry and Molecular Biology (IUBMB) Enzyme Nomenclature. A simple web-based query interface is provided, along with an advanced search engine for more complex Boolean queries. The WWW front-end is accessible at http://www.enzyme-database.org, from where downloads of the database as SQL and XML are also available. An associated form-based curatorial application has been developed to facilitate the curation of enzyme data as well as the internal and public review processes that occur before an enzyme entry is made official. Suggestions for new enzyme entries, or modifications to existing ones, can be made using the forms provided at http://www.enzyme-database.org/forms.php.

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Cite This Study

McDonald et al. (2008) studied this question.

synapsesocial.com/papers/69de7f054838c5c0bab0bfa8https://doi.org/10.1093/nar/gkn582
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