A multifactorial risk index incorporating ASA physical status, age, surgical procedure, and type effectively predicted major complications within 24 hours of anaesthesia (goodness-of-fit p=0.15).
Case-Control (n=3,374)
Can a multifactorial risk index predict major complications during or within 24 hours of anaesthesia in patients over 40 years of age?
A multifactorial risk index incorporating ASA physical status, age, surgical procedure, and type can predict major complications within 24 hours of non-cardiac anaesthesia in patients over 40.
p-value: p=0.15
The prediction of outcome of anaesthesia in patients over 40 years of age was assessed using a multifactorial index based on current preoperative factors recorded prospectively. The study was conducted using a representative sample of anaesthetizations (except for cardiac surgery) including 517 cases with major complication (occurring during or within 24 hours of anaesthesia) and a one in fifty random sample comprising 1538 cases without complication. A split sample approach was adopted and a logistic regression model was applied to two subsets of similar size. Four preoperative factors were significantly associated with the occurrence of complications: ASA physical status, age, surgical procedure (major/minor) and type (elective/emergency). Goodness-of-fit of the model was assessed using another sample of 332 cases with complication and a different subset of 987 cases without complication. The model fitted the data well (p = 0.15).
Tiret et al. (1988) conducted a case-control in Patients undergoing anaesthesia (n=3,374). Multifactorial risk index was evaluated on Major complication occurring during or within 24 hours of anaesthesia (p=0.15). A multifactorial risk index incorporating ASA physical status, age, surgical procedure, and type effectively predicted major complications within 24 hours of anaesthesia (goodness-of-fit p=0.15).