PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
June 17, 2005Stroke136 citations

Racial Disparities in Stroke Risk Factors

View Full Paper
DBDawn M. BravataCWCarolyn K. WellsBGBarbara Gulanski

Key Result

Black ethnicity was not independently associated with stroke after adjustment for income (adjusted OR 1.15; 95% CI 0.88-1.49), suggesting income may explain the association between ethnicity and stroke.

Key Points

  • To determine whether differences in socioeconomic status and the prevalence of established risk factors account for the relationship between race and stroke.
  • Analyzed cross-sectional data from the Third National Health and Nutrition Examination Survey (NHANES III, 1988–1994) comprising 11,163 noninstitutionalized Black and White adults aged 40 years or older.
  • Evaluated socioeconomic factors using education, health insurance, and income-to-poverty ratio alongside clinical and behavioral risk factors in multivariable models.
  • Stroke prevalence was 6% in both groups (Blacks: 160/2752 [6%]; Whites: 459/8411 [6%]; P=0.48), with Black individuals presenting higher rates of hypertension, treated diabetes, claudication, elevated C-reactive protein, and physical inactivity.
  • Ethnicity was independently associated with stroke after adjusting for 8 clinical risk factors (adjusted odds ratio [aOR], 1.32; 95% CI, 1.04 to 1.67).
  • Ethnicity was no longer independently associated with stroke after adjusting for income (aOR, 1.15; 95% CI, 0.88 to 1.49), whereas income retained an independent association (aOR, 0.89; 95% CI, 0.82 to 0.95).

Study Design

Type

Cross-Sectional (n=11,163)

Multicenter

Yes

Structured PICO

Does income explain the association between black ethnicity and higher stroke prevalence in the US population?

P
Population
11,163 black and white adults aged 40 years or older from the noninstitutionalized US population (NHANES III, 1988-1994), including 619 with a self-reported stroke history.
I
Intervention
Black ethnicity (observational exposure)
C
Comparator
White ethnicity (observational exposure)
O
Outcome
Association between ethnicity and stroke history, and the impact of income, education, insurance, and risk factors on this association

Income disparities may explain the observed association between black ethnicity and increased stroke prevalence in the US.

Main Result

Effect estimate: OR 1.15 (95% CI 0.88 to 1.49)

Absolute Event Rate: 6% vs 6%

p-value: p=0.48

Abstract

BACKGROUND AND PURPOSE: In the US, blacks have a higher incidence of stroke and more severe strokes than whites. Our objective was to determine if differences in income, education, and insurance, as well as differences in the prevalence of stroke risk factors, accounted for the association between ethnicity and stroke. METHODS: We used data from the Third National Health and Nutrition Survey (NHANES III), a cross-sectional sample of the noninstitutionalized US population (1988-1994), and included blacks and whites aged 40 years or older with a self-reported stroke history. Income was assessed using a ratio of income to US Census Bureau annual poverty threshold. RESULTS: Among 11 163 participants, 2752 (25%) were black and 619 (6%) had a stroke history (blacks: 160/2752 6%; whites: 459/8411 6%; P=0.48). Blacks had a higher prevalence of 5 risk factors independently associated with stroke: hypertension, treated diabetes, claudication, higher C-reactive protein, and inactivity; whites had a higher prevalence of 3 risk factors: older age, myocardial infarction, and lower high-density lipoprotein cholesterol. Ethnicity was independently associated with stroke after adjusting for the 8 risk factors (adjusted odds ratio, 1.32; 95% CI, 1.04 to 1.67). Ethnicity was not independently associated with stroke after adjustment for income and income was independently associated with stroke (adjusted odds ratios for: ethnicity, 1.15; 95% CI, 0.88 to 1.49; income, 0.89; 95% CI, 0.82 to 0.95). Adjustment for neither education nor insurance altered the ethnicity-stroke association. CONCLUSIONS: In this study of community-dwelling stroke survivors, ethnic differences exist in the prevalence of stroke risk factors and income may explain the association between ethnicity and stroke.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Bravata et al. (2005) conducted a cross-sectional in Stroke (n=11,163). Black ethnicity vs. White ethnicity was evaluated on Self-reported stroke history (OR 1.15, 95% CI 0.88 to 1.49, p=0.48). Black ethnicity was not independently associated with stroke after adjustment for income (adjusted OR 1.15; 95% CI 0.88-1.49), suggesting income may explain the association between ethnicity and stroke.

synapsesocial.com/papers/6a12c6edb761793c20c08907https://doi.org/10.1161/01.str.0000170991.63594.b6
Ask AI
Helpful
Bookmark
Share
View Full Paper