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January 23, 2026Discover Public Health0 citationsOpen Access

Navigating hypertensive disorders in pregnancy: a systematic review

DPDhanalakshmi PLKLakshmi KSPSreeja PA

Key Result

Innovative approaches and patient care interventions achieved around a 40% improvement in outcomes for women with hypertensive disorders of pregnancy.

Study Design

Type

Systematic Review (n=1,710)

Structured PICO

Do various interventions (pharmacological, lifestyle, mHealth) improve maternal and neonatal outcomes in pregnant women with or at risk of hypertensive disorders?

P
Population
Pregnant women with or at risk of hypertensive disorders of pregnancy (HDPs) from 6 RCTs
I
Intervention
Various interventions including antihypertensive medications, low-dose aspirin, calcium supplements, mHealth applications, exercise, and nutrition education
C
Comparator
Standard care or regular nursing
O
Outcome
Maternal and neonatal outcomes, including blood pressure control and preeclampsia rates

A systematic review of 6 RCTs highlights that early identification, standardized guidelines, and innovative approaches like mHealth and lifestyle interventions can improve outcomes in hypertensive disorders of pregnancy.

Limitations

  • Fragmented and inconsistent postpartum care
  • Some included studies had small sample sizes or unblinded designs

Abstract

One of the worldwide public health concerns is hypertension. Globally, 14% and in India, about 10.3% of maternal mothers are affected by hypertension, based on UNICEF data. Hypertensive disorders of pregnancy are the most prevalent complication in maternal mothers and neonates. Gestational hypertension, chronic (or preexisting) hypertension, preeclampsia, preeclampsia superimposed on chronic hypertension, and eclampsia are among the conditions collectively referred to as hypertensive disorders in Pregnancy (HDPs), which are defined by elevated blood pressure (BP) during the prenatal period. Assessing risk factors and implementing appropriate monitoring facilitates the prediction of hypertensive disorders in pregnancy, which impacts maternal and neonatal outcomes. This review discusses causes, etiology, pathophysiology, treatment, and management of high blood pressure during pregnancy. A thorough database search was conducted, including the Cochrane Library, Scopus, and PubMed. The articles were retrieved based on the search terms combining “Maternal health,” “Hypertensive disorders of pregnancy,” and “Treatment and management” from 2020 to 2025. Enhancing postpartum care is crucial for achieving health targets. Antihypertensive medications are essential for managing hypertensive disorders of pregnancy in women. Consultation is especially required on certain contentious topics, such as when to begin therapy and whether laboratory testing and cardiovascular risk assessment are necessary before starting treatment. Rob 2 tool is used for risk assessment for the randomized control trial systematic review. It is necessary to provide vital measures to help healthcare providers navigate the remote monitoring system, which can be used in hypertensive management. Hence, a technology-based mobile application is necessary for monitoring blood pressure to ensure effective management. Trial registration: PROSPERO 2025 CRD420251008080.

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Cite This Study

P et al. (2026) conducted a systematic review in Hypertensive disorders of pregnancy (n=1,710). Innovative approaches and patient care (including low-dose aspirin, mHealth, and lifestyle modifications) vs. Standard care was evaluated on Maternal and neonatal outcomes and blood pressure control. Innovative approaches and patient care interventions achieved around a 40% improvement in outcomes for women with hypertensive disorders of pregnancy.

synapsesocial.com/papers/6a13f1777753e742da5992e4https://doi.org/10.1186/s12982-025-01304-z
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