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September 1, 2003Journal of Cardiovascular Electrophysiology

Inducible ventricular flutter in old MI patients carried a 34% risk of ventricular tachycardia/fibrillation, comparable to SMVT (46%) and higher than noninducible patients (14%, P<0.005).

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Why the study?

Does inducible ventricular flutter during electrophysiologic studies predict the risk of ventricular tachycardia or ventricular fibrillation in patients with old myocardial infarction?

Population

344 consecutive patients with old myocardial infarction undergoing electrophysiologic studies.

Comparison

Induction of ventricular flutter during… vs Inducible ventricular fibrillation, inducible…

Design

Cohort

Follow-up

5 +/- 8 years

Key result

Inducible ventricular flutter in old MI patients carried a 34% risk of ventricular tachycardia/fibrillation, comparable to SMVT (46%) and higher than noninducible patients (14%, P<0.005).

Authors

SVSami ViskinMIMaya Ish‐ShalomEKEdward Koifman

Discussion

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Overview

Inducible ventricular flutter may indicate substantial arrhythmic risk in old MI; challenges consensus on its nonspecificity and leaves open need for prospective validation.

Study Design

Type

Cohort (n=344)

Multicenter

No

Structured PICO

Does inducible ventricular flutter during electrophysiologic studies predict the risk of ventricular tachycardia or ventricular fibrillation in patients with old myocardial infarction?

P
Population
344 consecutive patients with old myocardial infarction (MI) undergoing electrophysiologic (EP) studies (181 with previously documented spontaneous sustained ventricular arrhythmias, 61 with suspected ventricular arrhythmias, and 102 with neither).
I
Intervention
Induction of ventricular flutter during electrophysiologic studies
C
Comparator
Inducible ventricular fibrillation (VF), inducible sustained monomorphic ventricular tachycardia (SMVT), or noninducible
O
Outcome
Risk for ventricular tachycardia/ventricular fibrillation (VF) during follow-uphard clinical

Main Result

Absolute Event Rate: 34% vs 14%

p-value: p=< 0.005

In patients with old myocardial infarction, inducible ventricular flutter during EP studies carries a prognostic value comparable to that of sustained monomorphic ventricular tachycardia, indicating a high risk for future ventricular arrhythmias.

Cite This Study

Viskin et al. (2003) conducted a cohort in Myocardial infarction (n=344). Inducible ventricular flutter vs. Inducible SMVT, inducible VF, and noninducible patients was evaluated on Ventricular tachycardia/VF (p=< 0.005). Inducible ventricular flutter in old MI patients carried a 34% risk of ventricular tachycardia/fibrillation, comparable to SMVT (46%) and higher than noninducible patients (14%, P<0.005).

synapsesocial.com/papers/6a156a7fb2e0231f15827575https://doi.org/10.1046/j.1540-8167.2003.03082.x
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