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January 1, 2014BioMed Research InternationalOpen Access

Speckle-tracking and tissue-Doppler imaging detected significantly reduced LV systolic strain and strain rate in hypertensive patients compared to healthy controls during exercise (P<0.001).

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Why the study?

Do speckle-tracking and tissue-Doppler stress echocardiography detect subclinical LV impairment in hypertensive patients with normal ejection fraction compared to healthy controls?

Population

92 consecutive patients, comprising 46 hypertensive subjects with normal ejection fraction and 46 healthy…

Comparison

Speckle-tracking echocardiography and… vs Healthy controls.

Design

Cross-sectional

Key result

Speckle-tracking and tissue-Doppler imaging detected significantly reduced LV systolic strain and strain rate in hypertensive patients compared to healthy controls during exercise (P<0.001).

Authors

KHKai O. HenselAJAndreas JenkeRLRoman Leischik

Discussion

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Overview

May support strain imaging on stress echo for subclinical LV assessment in hypertension; leaves open prospective validation before practice change.

Study Design

Type

Case-Control (n=92)

Structured PICO

Do speckle-tracking and tissue-Doppler stress echocardiography detect subclinical LV impairment in hypertensive patients with normal ejection fraction compared to healthy controls?

P
Population
92 consecutive patients, comprising 46 hypertensive subjects with normal ejection fraction and 46 healthy controls.
I
Intervention
Speckle-tracking echocardiography (STE) and tissue-Doppler imaging (TDI) performed at rest and during bicycle exercise.
C
Comparator
Healthy controls.
O
Outcome
Global peak systolic LV circumferential strain (CS), longitudinal strain (LS), and longitudinal strain rate (SR) at rest and during exercise.surrogate

Main Result

p-value: p=<0.001

Speckle-tracking and tissue-Doppler imaging during stress echocardiography can detect early subclinical left ventricular systolic impairment in hypertensive patients with normal ejection fraction.

Cite This Study

Hensel et al. (2014) conducted a case-control in Arterial hypertension (n=92). Speckle-tracking echocardiography (STE) and tissue-Doppler imaging (TDI) vs. Healthy controls was evaluated on Global peak systolic LV circumferential strain (CS), longitudinal strain (LS), and longitudinal strain rate (SR) (p=<0.001). Speckle-tracking and tissue-Doppler imaging detected significantly reduced LV systolic strain and strain rate in hypertensive patients compared to healthy controls during exercise (P<0.001).

synapsesocial.com/papers/6a157688b2e0231f15828670https://doi.org/10.1155/2014/472562
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