Studying specific phenotypes and genotypes across ethnic groups is proposed to better advance the understanding of blood pressure regulation than studies focused solely on race.
The paper highlights the limitations of race-based hypertension research and advocates for a genotype- and phenotype-driven approach to understand interindividual and interethnic variability in blood pressure regulation.
Hypertension is more frequent and more severe in some Black populations. Although many studies have focused on hypertension in black people in an attempt to understand the genetic and environmental factors that regulate blood pressure, this approach has not been productive. Study of the relationship between specific phenotypes and genotypes, both within and across ethnic groups, is more likely to advance our understanding of the regulation of blood pressure than studies focused on race and blood pressure.
Stein et al. (2001) conducted an editorial in Hypertension. Studying specific phenotypes and genotypes across ethnic groups is proposed to better advance the understanding of blood pressure regulation than studies focused solely on race.
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