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November 1, 2005Psychosomatic Medicine

Baseline low perceived social support in post-MI patients was associated with a higher risk of death or nonfatal MI compared to patients without LPSS (23% vs 10%; HR 1.74-2.39).

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Why the study?

Does low perceived social support increase the risk of death or recurrent MI in post-MI patients, and does psychosocial intervention improve these outcomes?

Population

1,911 post-myocardial infarction patients, comprising 1,503 patients with low perceived social support…

Comparison

Psychosocial intervention vs Usual care and a comparison group of acute…

Design

Cohort

Follow-up

average 29 months

Key result

Baseline low perceived social support in post-MI patients was associated with a higher risk of death or nonfatal MI compared to patients without LPSS (23% vs 10%; HR 1.74-2.39).

Authors

MBMatthew M. BurgJBJohn C. BarefootLBLisa Berkman

Discussion

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Overview

LPSS identifies higher-risk post-MI patients; leaves open whether baseline-stratified psychosocial interventions improve outcomes.

Study Design

Type

Cohort (n=1,911)

Structured PICO

Does low perceived social support increase the risk of death or recurrent MI in post-MI patients, and does psychosocial intervention improve these outcomes?

P
Population
1,911 post-myocardial infarction patients, comprising 1,503 patients with low perceived social support (LPSS) enrolled in the ENRICHD clinical trial, and a comparison group of 408 concurrently enrolled acute myocardial infarction patients without depression or LPSS.
I
Intervention
Psychosocial intervention
C
Comparator
Usual care (treatment assignment) and a comparison group of acute myocardial infarction patients without depression or LPSS
O
Outcome
Combined end point of death or nonfatal myocardial infarction at average 29-month follow-upcomposite

Main Result

Effect estimate: HR 1.74-2.39

Absolute Event Rate: 23% vs 10%

Baseline low perceived social support is an independent predictor of death and recurrent MI in post-MI patients, and psychosocial intervention effects may depend on baseline support levels.

Limitations

  • Post hoc analysis

Cite This Study

Burg et al. (2005) conducted a cohort in Post-myocardial infarction (n=1,911). Low perceived social support (LPSS) / Psychosocial intervention vs. No LPSS or depression (MI comparison group) was evaluated on Combined end point of death or nonfatal MI (HR 1.74-2.39). Baseline low perceived social support in post-MI patients was associated with a higher risk of death or nonfatal MI compared to patients without LPSS (23% vs 10%; HR 1.74-2.39).

synapsesocial.com/papers/6a183050fb37ff6cad6f953ehttps://doi.org/10.1097/01.psy.0000188480.61949.8c
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