Why the study?
Does a Mediterranean/low-carbohydrate diet with or without physical activity improve body fat redistribution compared to a low-fat diet in sedentary adults with abdominal obesity or dyslipidemia?
Population
278 sedentary adults with abdominal obesity or dyslipidemia, mean age 48 years, 89% men, BMI 30.8 kg/m2, in…
Comparison
Mediterranean/low-carbohydrate diet + 28 g… vs Isocaloric low-fat diet with or without added…
Design
RCT, randomized
Follow-up
18 months
Key result
Adding moderate physical activity to dietary interventions significantly decreased visceral adipose tissue compared to diet alone (mean difference -6.67 cm2; 95% CI -14.8 to -0.45).
Authors
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Supports adding moderate activity to diet for greater VAT loss in abdominal obesity; extends diet-only trials by confirming independent benefit.
RCT (n=278)
randomized
No
Does a Mediterranean/low-carbohydrate diet with or without physical activity improve body fat redistribution compared to a low-fat diet in sedentary adults with abdominal obesity or dyslipidemia?
Mean Difference: -6.67 (95% CI -14.8–-0.45)
A Mediterranean/low-carbohydrate diet combined with physical activity uniquely mobilizes specific atherogenic and diabetogenic ectopic fat depots independent of weight loss.
Gepner et al. (2017) conducted an RCT in Sedentary adults with abdominal obesity or dyslipidemia (n=278). Mediterranean/low-carbohydrate diet + walnuts with/without physical activity vs. Isocaloric low-fat diet with/without physical activity was evaluated on Visceral adipose tissue (VAT) (MD -6.67 cm2, 95% CI -14.8 to -0.45). Adding moderate physical activity to dietary interventions significantly decreased visceral adipose tissue compared to diet alone (mean difference -6.67 cm2; 95% CI -14.8 to -0.45).
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