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December 1, 2009BMC Family Practice51 citationsOpen Access

Cardiovascular risk factor assessment after pre-eclampsia in primary care

MNMarie-Elise NijdamMTMonique R TimmermanAFArie Franx

Key Result

Women with a history of pre-eclampsia were more likely to have their blood pressure checked after pregnancy compared to controls (57.1% vs. 12.0%), though overall follow-up remained insufficient.

Study Design

Type

Cohort (n=185)

Multicenter

Yes

Structured PICO

Does a history of pre-eclampsia lead to adequate cardiovascular risk factor assessment in primary care compared to uncomplicated pregnancy?

P
Population
185 women (35 with a history of pre-eclampsia and 150 with uncomplicated pregnancies) followed for a mean of 2.5 to 2.9 years postpartum to assess cardiovascular risk factor management in primary care.
E
Exposure
History of pre-eclampsia
C
Comparator
Uncomplicated pregnancy
O
Outcome
Frequency and timing of blood pressure, cholesterol, and glucose measurements, and vascular diagnoses after pregnancy

Despite the known increased cardiovascular risk after pre-eclampsia, primary care follow-up for cardiovascular risk factors in these women is insufficient and undeveloped.

Main Result

Absolute Event Rate: 57.1% vs 12%

p-value: p=<0.001

Limitations

  • Small number of pre-eclampsia cases limits wide extrapolation due to limited precision.
  • Reliance on the quality of registration by general practitioners, which may lead to systematic underestimation if negative findings are not reported.
  • Blood pressure check-ups performed by other providers (e.g., gynaecologists, midwives) or patients themselves might not be captured in the medical records.
  • Small number of PE cases
  • Reliance on the quality of registration by GPs
  • Potential underestimation if GPs did not report negative findings
  • Some check-ups might have been performed by other providers and not recorded in GP charts

Abstract

BACKGROUND: Pre-eclampsia is associated with an increased risk of development of cardiovascular disease later in life. It is not known how general practitioners in the Netherlands care for these women after delivery with respect to cardiovascular risk factor management. METHODS: Review of medical records of 1196 women in four primary health care centres, who were registered from January 2000 until July 2007 with an International Classification of Primary Care (ICPC) code indicating pregnancy. Records were searched for indicators of pre-eclampsia. Of those who experienced pre-eclampsia and of a random sample of 150 women who did not, the following information on cardiovascular risk factor management after pregnancy was extracted from the records: frequency and timing of blood pressure, cholesterol and glucose measurements--and vascular diagnoses. Additionally the sensitivity and specificity of ICPC coding for pre-eclampsia were determined. RESULTS: 35 women experienced pre-eclampsia. Blood pressure was more often checked after pregnancy in these women than in controls (57.1% vs. 12.0%, p<0.001). In 50% of the cases blood pressure was measured within 3 months after delivery with no further follow-up visit. A check for glucose and cholesterol levels was rare, and equally frequent in PE and control women. 20% of the previously normotensive women in the PE group had hypertension at one or more occasions after three months post partum versus none in the control group. The ICPC coding for pre-eclampsia showed a sensitivity of 51.4% and a specificity of 100.0%. CONCLUSION: Despite the evidence of increased risk of future cardiovascular disease in women with a history of pre-eclampsia, follow-up of these women is insufficient and undeveloped in primary care in the Netherlands.

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Cite This Study

Nijdam et al. (2009) conducted a cohort in Pre-eclampsia (n=185). History of pre-eclampsia vs. Uncomplicated pregnancy was evaluated on Blood pressure measurement after pregnancy (p=<0.001). Women with a history of pre-eclampsia were more likely to have their blood pressure checked after pregnancy compared to controls (57.1% vs. 12.0%), though overall follow-up remained insufficient.

synapsesocial.com/papers/6a21772b96850e9b858b7805https://doi.org/10.1186/1471-2296-10-77
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