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May 1, 2004Journal of Chemical Research3 citationsOpen Access

Molecular Recognition in β-Lactams: The Crystal Packing in 4-Sulfonyl β-Lactams

ABAmit BasakIndian Institute of Technology KharagpurSBSubhendu Sekhar BagIndian Institute of Technology GuwahatiPMP.A. MazumdarUniversity of Calcutta

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Abstract

Single crystal X-ray structures of 4-phenyl sulfonyl 2-azetidinone 1, a 1:2 conglomerate of the corresponding 3-methyl (trans) and 3,3-dimethyl derivatives 2A and 2B/2C respectively and 3-acetoxymethyl 1,4-diphenyl 2-azetidinone 3 revealed interesting variation in crystal packing dictated by H-bonding and hydrophobic interactions which may be responsible for molecular recognition in β-lactams.

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Cite This Study

Basak et al. (2004) studied this question.

synapsesocial.com/papers/6a7a5362123479a499f37cf6https://doi.org/10.3184/0308234041639647
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