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January 1, 2011Circulation Journal0 citationsOpen Access

Circulation Journal Awards for the Year 2010

HSHiroaki Shimokawa

Key Result

Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption significantly improved left ventricular ejection fraction at 3 months compared to incomplete elimination in patients with severe heart failure.

PICO

P
Population
18 patients with severe heart failure (NYHA class 3 or 4, LVEF <30%) who underwent immunoadsorption to eliminate cardiodepressant IgG3 autoantibodies.
E
Exposure / Comparator
Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption vs Incomplete elimination
O
Primary Outcome
Increase in left ventricular ejection fraction (LVEF) at 3 months, p=<0.01

Main Result

p-value: p=<0.01

Abstract

The aim of these Awards is to recognize papers published in 2010, both clinical and experimental studies, that were highly appreciated by the Editorial Team. The selection process comprises 2 steps. First, from the 277 original papers published in the Journal in 2010, our 33 Japanese Associate Editors selected papers with a high scientific level in their respective fields, and second, the 2 Associate Editorial Teams (16 on 1 team and 17 on the other) further evaluated the selected papers in terms of originality, contribution to cardiovascular science, manner of paper preparation, and future possibilities.

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Cite This Study

Hiroaki Shimokawa (2011) conducted an editorial in Severe Heart Failure (n=18). Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption vs. Incomplete elimination was evaluated on Increase in left ventricular ejection fraction (LVEF) at 3 months (p=<0.01). Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption significantly improved left ventricular ejection fraction at 3 months compared to incomplete elimination in patients with severe heart failure.

synapsesocial.com/papers/6a9ac99344c3282f559e457dhttps://doi.org/10.1253/circj.cj-88-0006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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