Supplementary Figure S4 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma
Key Points
Main finding indicates RAS(ON) inhibition affects PDAC tumor responses by modifying the immune landscape.
The study suggests that early immune changes correlate with T-cell activity in pancreatic tumor models.
Inhibition of RAS(ON) leads to notable shifts in the PDAC microenvironment, impacting tumor behavior.
Understanding these immune dynamics could enhance therapeutic strategies for pancreatic cancer.
Abstract
Supplementary Figure S4: RAS(ON) multi-selective inhibition results in early changes to the PDAC tumor immune microenvironment
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Supplementary Figure S4 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma | Synapse