Abstract Atomic force microscopy (AFM) is widely used to measure surface topography of solid, soft, and living matter at the nanoscale. Moreover, by mapping forces as a function of distance to the surface, AFM can provide a wealth of information beyond topography, with nanomechanical properties as a prime example. Here, a method based on photothermal off‐resonance tapping (PORT) is presented to increase the speed of such force spectroscopy measurements by at least an order of magnitude, thereby enabling high‐throughput, quantitative nanomechanical mapping of a wide range of materials. Specifically, photothermal actuation is used to modulate the position of the AFM probe at frequencies that far exceed those possible with traditional actuation by piezo‐driven z scanners. Understanding and accounting for the microscale thermal and mechanical behavior of the AFM probe, the study determines the resulting probe position at sufficient accuracy to allow rapid and quantitative nanomechanical examination of polymeric and metallic materials.
Gunstheimer et al. (Thu,) studied this question.
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