The skin plays a dual role in topical and transdermal drug delivery, serving as both a key Focus and a significant barrier.Despite its advantages, the system is hindered by the low absorption rate of drugs through the skin barrier corneum,a important barrier in effective delivery. Ethosomes in novel Vesicles play a crucial role in transdermal drug delivery by encapsulating medications and facilitating their absorption transdermally. show Notable impact Pertaining to Medicine penetration through the biological membrane.Ethosomes are phospholipid based elastic nanovesicles containing a high content of ethanol(20-45%).Ethosomal systems have shown superior efficacy During delivery substances to the skin, outperforming Traditional liposomes and Alocohal based solutions regarding of both quantity and depth of penetration.Ethosomes carriers facilitate enhanced delivery bioactive molecules across skin plus cellular barriers presenting opportunities and challenges for developing innovative therapies.
Riddhi et al. (Thu,) studied this question.