Supplementary Fig. S17 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer

Key Points

• Biallelic inactivation of TP53 was observed in different gastric cancer types, highlighting genetic variation.
• Samples showed significant diversity in TP53 mutations between intestinal and diffuse gastric cancer types.
• Genomic analysis examined the characteristics of intestinal metaplasia, linking it to gastric cancer progression.
• Findings suggest that understanding these differences may enhance cancer diagnosis and treatment strategies.