Midodrine exposure trends and outcomes reported to United States poison centers: 2000–2023

Key Points

• Midodrine exposure trends indicate increased reporting to poison centers over time, suggesting heightened awareness.
• The analysis highlights significant associations with adverse outcomes, including hypertension and bradycardia.
• Characterization of exposures utilizes data from multiple poison centers, ensuring a comprehensive view of midodrine's effects.
• The trends underscore the importance of monitoring vasoconstrictive agents like midodrine in clinical practice.