Figure S14 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• Pharmacological modulation of ppar-δ inhibits metastasis in pancreatic cancer, indicating its pivotal role.
• Meta-analysis showed enhanced invasion and metastasis in vivo, with the highly metastatic PDX CTCA model.
• Research utilized advanced techniques in pharmacological modulation to study ppar-δ effects on tumor behavior.
• Findings suggest targeting ppar-δ may offer new therapeutic avenues for pancreatic cancer management.