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This is a Cross-Sectional Study study.

September 10, 2025Open Access

Determinants of Non-Adherence to Anti-Tuberculosis Treatment in a Public Primary Healthcare Clinic in South Africa: Improving the Quality of Long-Term Care

Key Points

Non-adherence to anti-tuberculosis treatment significantly affects tuberculosis treatment success rates and increased healthcare costs.
Out of 65 participants, 45 (69.23%) were adherents, revealing challenges in treatment compliance.
Cross-sectional study collected data through structured interviews, highlighting barriers like distance to clinics and lack of family support.
Addressing multifactorial factors is crucial for improving treatment adherence and eradicating tuberculosis.

Abstract

Non-adherence to anti-tuberculosis treatment remains a major obstacle to increasing tuberculosis treatment success rates and enhancing healthcare expenditure. The aim of this study was to identify determinants contributing to non-adherence to anti-tuberculosis treatment in a public primary healthcare clinic in South Africa. A cross-sectional study was carried out to collect data from 65 participants using face-to-face interviews with a structured questionnaire. Data were analyzed using SPSS. Of the 65 participants interviewed, 41 (63.08%) were males and 24 (36.92%) were females. A total of 45 (69.23%) were adherents and 20 (30.77%) were non-adherents. Gender was the major predictor of non-adherence with more males committed to treatment than females with a significant association (X2 = 65.00 and p of <0.001). The major contributing factors to non-adherence were long dis-tances to the clinics, a lack of family support, and unemployment. Comprehensive programs addressing these multifactorial factors are needed for successful treatment and eradication of tuberculosis.

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