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Quantitative susceptibility mapping (QSM) is an emerging technique and may be utilized to assess neurodevelopmental disabilities characterized by insufficient iron content and myelination. In this study, a total of 23 full-term and 12 preterm newborns were studied using QSM. Compared to full-term, mean regional susceptibility of preterm newborns was significantly higher in the parietal white matter and was significantly lower in the frontal gray matter. This may be indicative of a regional deficit in iron deposition and myelination of the preterm newborn brain, and suggest that QSM may be used to identify early evidence of impaired neurodevelopment.
Park et al. (Wed,) studied this question.