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Deuterium metabolic imaging (DMI) is a new way to track brain metabolism. We present initial results from 3 volunteers scanned with a new 18-element 2H + 2-element 1H array coil on a Siemens 7T Terra scanner. We utilised our array’s high SNR to track metabolism by whole-brain 3D DMI after drinking 6,6’-2H2-glucose (Glc). Signals from HDO, Glc, Glx and Lac were visible over 2hrs at 5min temporal and 6.9mL spatial resolution. We also ran 2.9mL 3D DMI. We achieved HDO SNR of 43 in 13min, which compares favourably published SNR=13 in 10min at 9.4T1 and ~50 in 28min at 7T.2
Zhang et al. (Wed,) studied this question.
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