Formulation and Evaluation Herbal Gel from Psidium Guajava and Jasminium Officinali for Mouth Ulcer Treatment

Abstract: India has long employed traditional or herbal medicine to diagnose, treat, and prevent illness. The study's objective was to create and assess a herbal gel that contained extract from jasmine officinale and Psidium guajava for the treatment of mouth ulcers. Herbal gel made using powdered extracts of Psidium guajava and Jasminum officinale at varying concentrations. Psidium guajava has high antifungal and antibacterial action and is used to treat a number of illnesses, including diabetes mellitus, diarrhea, rheumatism, wounds in the throat, and coughs. Tannins, flavonoids, triterpene, quercetin, pentacycline, triterpenoids, gujanoic acid, saponins, carotenoids, lectin, ellugic acid, sitosterol, and oleanolic acid are found in Psidium guajava leaves, whereas the properties of Jasmine Officinale include analgesic, antioxidant, anti-inflammatory, stomachic, astringent, stimulating, and sedative effects. Alkaloids, tannins, terpenoids, glycosides, steroids, essential oil, and saponin are among its constituents.Guava and jasmine leaf extracts, Carbopol 934, propylene glycol, propyl paraben, methyl paraben, triethanolamine, and distilled water were used to make the herbal gel formulation. To keep the pH between 7 and7.5, triethanolamine was added. The evaluation's viscosity, homogeneity, PH, and spreadability parameters. The gel strength and extruadability were ascertained.The results indicate that all assessment parameters found to be acceptable with the normal range were discovered in the optimized herbal gel formulation containing extracts from guava and jasmine leaves. For the treatment of oral ulcers, the herbal formulation proved to be more stable, safe, and successful than the synthetic formulation.