May 31, 2024Open Access

SIRT2-dependent DKK1 deacetylation aggravates polycystic ovary syndrome by targeting the TGF-β1/Smad3 signaling pathway

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Abstract

Background Polycystic ovarian syndrome (PCOS) is a prevalent metabolic and endocrine condition in females of reproductive age. This work was to discover the underlying role of Dickkopf 1 (DKK1) and its putative regulating mechanism in P COS.

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Chen et al. (Fri,) studied this question.

synapsesocial.com/papers/68e6763ab6db643587600d46 https://doi.org/https://doi.org/10.1080/09513590.2024.2353733

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