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May 2, 2024JAMA Oncology61 citationsOpen Access

Measurable Residual FLT3 Internal Tandem Duplication Before Allogeneic Transplant for Acute Myeloid Leukemia

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LDLaura W. DillonGGGege GuiNRNiveditha Ravindra

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Abstract

Persistence of FLT3 internal tandem duplication (ITD) in adults with acute myeloid leukemia (AML) in first complete remission (CR) prior to allogeneic hematopoietic cell transplant (HCT) is associated with increased relapse and death after transplant, but the association between the level of measurable residual disease (MRD) detected and clinical outcome is unknown.

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Dillon et al. (2024) studied this question.

synapsesocial.com/papers/68e6bbd2b6db64358763c958https://doi.org/10.1001/jamaoncol.2024.0985
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