A-70 | Impact of Iron Deficiency Anemia On Percutaneous Coronary Intervention Outcomes Among Young Women With Acute Coronary Syndrome: A Nationwide Propensity Matched Analysis 2016 -2020

A strong association exists between anemia and poor outcomes following percutaneous intervention (PCI) for acute coronary syndromes (ACS) patients. We aim to study the implications of Iron Deficiency Anemia (IDA) in outcomes of PCI in young females undergoing PCI due to limited studies in this population. Methods: Utilizing the National Inpatient Sample database (2016-2020) and ICD-10 codes, we classified young females (18-44 years) diagnosed with ACS undergoing PCI into 2 groups: with and without IDA. Outcomes, including all-cause mortality (ACM), procedural complications, length of stay (LOS), and hospitalization cost, were studied. Results: 1230 patients were identified with and without IDA. IDA group had more Blacks and fewer Asians/Pacific Islanders and Hispanics compared to the non-IDA group. Patients with IDA were more likely to have complicated hypertension (27.2% vs. 19.9%), diabetes with chronic complications (32.5% vs. 24%), alcohol abuse (4.1% vs. 2%), drug abuse (10.2% vs. 5.7%), prior TIA/stroke (6.9% vs. 3.3%) and less likely to have diabetes without complications (13.8% vs. 20.7%), hyperlipidemia (47.6% vs. 56.5%), peripheral vascular disease (3.3% vs. 6.6%) all p<0.05. Higher odds of ACM (aOR 1.804, 95% CI 0.22-14.8, p=0.58) and post-PCI adverse events (aOR 1.46, 95% CI 0.58-3.7, p=0.42) were noted in the IDA cohort, although the association was not statistically significant. The mean LOS in the IDA cohort was 3 days, compared to 2 days in the non-IDA group. Conclusions: Young females with IDA admitted for ACS undergoing PCI were found to have a higher LOS, and the odds of outcomes were comparable in young females with vs without IDA. A. Sawhney, A. S. Mohammed, H. Ahmed, S. N. Thiagarajan, S. Vanani, P. Sevella, A. A. Mohd, D. Bhatty, R. Rukhshan, T. Sumera, K. Prajapati, R. Desai, Nothing to disclose.