Abstract 3121: Gender And Racial Differences In Complications Of Coronary Angiography

Background: Coronary angiography is an effective diagnostic tool for assessing coronary lesions and visualizing vascularization. Although research has been conducted on the occurrence of complications of the procedure, limited research is available comparing the occurrence of postoperative complications between various patient populations. Our study aims to bridge this gap by assessing the gender and racial disparities in outcomes of coronary angiography. Methods: Data was obtained from TriNetX, a national database of deidentified medical records with IRB pre-approval. Two distinct pairs of cohorts were identified - patients that underwent coronary angiography divided by gender (male and female) and race (White and Black). Cohorts were matched with a propensity score model. Four complications were studied 0-3 days post procedure: acute myocardial infarction (MI), cerebral infarction, arrhythmias, and acute renal failure. Statistical analysis included risk differences with a significance value of p ≤ 0.05. Results: (*incidence values included in parentheses are percentages) Gender: We identified 162,408 male patients and 102,461 female patients that had a coronary angiography performed. No significant difference between male and female patients was observed in the incidence of stroke (0.422 vs 0.482, p = 0.0820). Males had a higher incidence of MI (9.251 vs 7.547, p ≤ 0.001), arrhythmias (3.786 vs 2.877, p ≤ 0.001), and acute renal failure (1.385 vs 1.19, p = 0.003) Race: We identified 178,024 white patients and 24,616 black patients that had a coronary angiography performed. No significant difference between white and black patients was observed in the incidence of MI (8.485 vs 8.215, p = 0.2808). White patients had a higher incidence of arrhythmias (3.077 vs 2.722, p = 0.0191), whereas black patients had a higher likelihood of stroke (0.401 vs 0.666, p ≤ 0.001) and acute renal failure (0.335 vs 0.781, p ≤ 0.001). Conclusion: Gender and racial differences in complications of coronary angiography are evident within 72 hours (about 3 days) of the procedure. Male and Black patients had a higher risk of life-threatening complications. Physicians can use this information for postprocedural monitoring of high-risk patients to improve outcomes.