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Staphylococcus epidermidis is one of the bacteria that causes acne. infections can be treated by using natural antibiotics. galangal rhizome (Kaempferia galanga L.) contains chemical compounds including flavonoids, saponins, tannins, alkaloids and terpenoids/steroids where these active compounds have an antibacterial function that can overcome acne problems on the surface of the skin. Galangal rhizome ethanol extract gel preparations were made with 3 variations of concentration (10%, 15% and 20%). The aim of this research was to determine whether the ethanol extract gel preparation of kencur rhizome (Kaempferia galanga L.) had antibacterial activity against Staphylococcus epidermidis and to determine the physical quality of the gel preparation. The method used is an experimental laboratory which is useful for determining the effect of ethanol extract of kencur rhizomes with concentrations of 10%, 15% and 20% on Staphylococcus epidermidis bacteria in gel preparations. The antibacterial test was carried out using the well diffusion method. The antibacterial test results with concentrations of 10%, 15% and 20% respectively were 13.68; 13.60 ; 14.24 mm has an influence on the inhibition zone of Staphylococcus epidermidis bacteria. The research results showed that a concentration of 20% had the highest bacterial inhibitory power.
Hotimah et al. (Tue,) studied this question.