An Overview of Osteoporosis and Possible Treatment Approaches

Osteoporosis is most prevalent in postmenopausal women and is a widespread condition that impacts millions of individuals worldwide. A decrease in bone mineral density and elevated susceptibility to fractures as a result of bone architecture deterioration are the primary attributes of osteoporosis. Due to the challenging nature of treating osteoporosis as a chronic condition, further research into innovative and efficacious therapeutic and animal models that aim to test these drug approaches is necessary. Numerous preclinical and clinical studies have focused on identifying the most efficacious therapeutic approaches for this condition. Various types of treatment are available for osteoporosis, which vary based on particular characteristics of the patient's condition. These comprise a combination of recently developed and established medications. This review focuses on novel therapeutic approaches for osteoporosis and their corresponding mechanisms of action, pathophysiology, the animal model, and the parameters that are assessed.