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March 19, 2024EBioMedicine30 citationsOpen Access

Hepatotoxicity in patients with non-small cell lung cancer treated with sotorasib after prior immunotherapy: a comprehensive clinical and pharmacokinetic analysis

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SESophie M. ErnstMHMaaike M. HofmanTHTessa E. van der Horst

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Abstract

Sotorasib given after immunotherapy could put patients at increased risk of hepatotoxicity. Therefore, there is a need to gain insight into the potential correlation between anti-PD-(L)1 treatment, anti-PD-(L)1 concentrations, sotorasib concentrations, and the incidence of hepatotoxicity during sotorasib.

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Cite This Study

Ernst et al. (2024) studied this question.

synapsesocial.com/papers/68e734edb6db6435876ae379https://doi.org/10.1016/j.ebiom.2024.105074
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