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An inherited bleeding problem is hemophilia. Recombinant clotting factor VIII or factor IX and immunosuppressive drugs are used to treat hemophilia A or B to stop the development of alloantibodies and inhibitors. Treatment of hemophilia is a problem due to the formation of inhibitors to these factors. Patients with inhibitors are treated with activated recombinant factor VII and plasma-derived activated prothrombin complex concentrate. Treatment differs depending on the circumstance since bleeding is more likely to occur in cases of pregnancy, surgery, and cancer. The major topic of this study was to assess healthy persons' awareness of hemophilia and their familiarity with this condition from birth. 30 people from rural Sindh participated in a cross-sectional, random study. All participants were asked regular questions about their awareness of the illness, and SPSS software was used to analyze the data. There is currently no long-term or permanent treatment for hemophilia. Hemophilia may be temporarily cured by factor replacement. The direction of gene therapy or stem cell treatment, both of which are under development, may lead to a permanent cure. Previous research has shown that gene therapy seldom succeeds in curing patients for many months without the requirement for recombinant factor replenishment. To obtain a long-lasting and permanent cure for hemophilia, more adjustments to the treatment plan are necessary.
Unar et al. (Wed,) studied this question.