Efficacy of Fibro-Gide® in coronally advanced flap for the treatment of multiple gingival recession: A prospective clinical study

Abstract Aim: The study aims to compare connective tissue graft (CTG) with Fibro-Gide ® as an adjunct to the coronally advanced flap (CAF) technique for treating class I and class II gingival recession based on Miller’s classification. Materials and Methods: A total of 30 participants with bilateral Miller’s class I or class II multiple gingival recession contributing to 60 multiple gingival recession sites were enrolled in this prospective clinical study. Recession sites were categorized into two groups. Group 1 (CAF+ CTG; n = 30 sites) and group 2 (CAF+ Fibro-Gide ® ; n = 30 sites). Clinical parameters, such as gingival recession depth (GRD), probing depth (PD), clinical attachment level (CAL), gingival recession width (GRW), and keratinized tissue (KT) were evaluated at baseline, 3 months, and 12 months. Statistical analysis was performed for intergroup comparison using an independent t test and for intra-group comparison using paired t test. Results: At baseline, the mean GRD for groups 1 and 2 were 3.5 ± 0.8 and 3.4 ± 0.8, whereas GRW for group 1 and group 2 were 3.1 ± 0.1 and 3.1 ± 0.2 respectively. At 12-month follow-up, the reduction in GRD and GRW was statistically significant. The gain of KT accounted to 3.9 ± 5.5 and 3.0 ± 0.8 in group 1 and group 2, respectively, but CAL showed a significant decrease from 5.4 ± 1.02 and 5.4 ± 1.03 to 2.3 ± 0.7 and 2.4 ± 0.7 in group 1 and group 2, respectively. Conclusion: Fibro-Gide ® along with CAF improved gingival recession in terms of depth and width as comparable with those of CTG. In terms of KT, CTG has better long-term stability than Fibro-Gide ® when combined with the CAF technique in treating multiple gingival recessions.