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January 14, 2026Open Forum Infectious DiseasesOpen Access

P-393. Treatment Switch among Medicare-insured People with HIV and Gaps in Care

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Authors

SLS. LiMCMary J. ChristophUMUche Mordi

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Overview

Retrospective analysis shows treatment switch in HIV patients with care gaps, indicating ART choice matters.

Key Points

  • To describe the treatment switch among Medicare-insured individuals with HIV and significant gaps in care.
  • Retrospective cohort study of treatment-experienced HIV patients aged 18+ insured by Medicare.
  • Examined treatment switch by antiretroviral therapy regimen in patients with 90-day care gaps or low adherence.
  • Followed patients from ART initiation until switch, analyzing treatment persistence with Kaplan-Meier curves.
  • Of 30,205 participants, 7,227 had ≥90-day gaps before ART initiation and 6,140 had low adherence.
  • Patients on BIC/FTC/TAF had the lowest likelihood of switching regimens compared to others.
  • HRs for switching were higher for DTG/ABC/3TC and MTRs than BIC/FTC/TAF in both cohorts.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6966e72413bf7a6f02bff758https://doi.org/10.1093/ofid/ofaf695.610
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