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January 14, 2026Journal of Cardiovascular Medicine1 citations

Prognostic value of right ventricle–pulmonary artery coupling in intensive cardiac care unit

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AGAlma GrossiARAmelia RaveraFVFrancesco Vigorito

Key Points

  • The aim was to investigate the prognostic role of right ventricle–pulmonary artery coupling in ICU patients.
  • Retrospective analysis of 1,606 patients from an internal database
  • Assessment of TAPSE/sPAP ratio using echocardiography
  • Propensity matching for patient selection
  • TAPSE/sPAP ratio < 0.51 associated with 30-day mortality
  • Odds ratio of 1.76 (95% CI 1.12–2.66; P = 0.014) for 30-day mortality
  • No significant association with long-term mortality (hazard ratio 1.3, P = 0.2)

Abstract

Background The modern intensive cardiac care unit (ICCU) demands new, reliable prognostic tools. We aimed to investigate the prognostic role of the right ventricle–pulmonary artery (RV-PA) coupling, assessed by the echocardiographic ratio between the tricuspid annular plane systolic excursion (TAPSE) and the systolic pulmonary artery pressure (sPAP), in an unselected population admitted to the ICCU. Methods and results One thousand six hundred and six patients were retrospectively identified from an internal database. After propensity matching, a TAPSE/sPAP ratio less than 0.51 was strongly associated with 30-day mortality odds ratio (OR) 1.76, 95% confidence interval (CI) 1.12–2.66; P = 0.014, but not with long-term mortality (hazard ratio 1.3, 95% CI 0.87–1.89; P = 0.2). Major findings In an unselected, mixed ICCU population, the RV coupling assessment is feasible and strongly associated with 30-day mortality.

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Cite This Study

Grossi et al. (2025) studied this question.

synapsesocial.com/papers/6966f31513bf7a6f02c009d6https://doi.org/10.2459/jcm.0000000000001818
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