Peak donor troponin ≥75th percentile was associated with increased 1-year graft loss (HR 1.22; P=0.045) in pediatric heart transplant recipients.
Does elevated peak donor troponin or donor troponin trend predict worse 1-year post-transplant graft survival in pediatric heart transplant recipients?
Elevated peak donor troponin (>0.66 ng/mL) is associated with worse 1-year graft survival in pediatric heart transplants, but donor troponin trends over time are not prognostic.
Absolute Event Rate: 0% vs 0%
Background Donor discard rates for pediatric heart transplant (HT) remain high (≈40%), often driven by concerns about elevated donor troponin levels. This study evaluated the association between peak donor troponin levels, donor troponin trends, and post transplant survival among pediatric HT recipients. Methods Children (aged 0.66 ng/mL) correlates with donor hemodynamic instability and predicts worse 1‐year post transplant graft survival, whereas troponin trajectories are not prognostic.
Amdani et al. (Thu,) reported a other. Peak donor troponin ≥75th percentile was associated with increased 1-year graft loss (HR 1.22; P=0.045) in pediatric heart transplant recipients.
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