ABSTRACT Reliable acquisition of surface electromyography (sEMG) signals requires stretchable electrode arrays with high conductivity, robust mechanics, and low crosstalk, but such a combination has not yet been achieved in existing systems. Here, we present a multilayer stretchable microelectrode array patch (MEAP‐S) that integrates photolithographically patterned gold microelectrodes with an ultrathin SEBS dielectric layer. MEAP‐S achieves high conductivity (> 10 5 S m − 1 ), stretchability up to 100%, and densities of 100 channels cm − 2 , while effectively suppressing inter‐channel interference. The device delivers stable, noise‐robust performance with signal‐to‐noise ratios above 27 dB under strain and during long‐term wear. Human studies demonstrate superior comfort and biocompatibility compared with Ag/AgCl electrodes, along with accurate decoding of complex hand gestures from high‐density sEMG maps. These results establish MEAP‐S as a scalable and versatile platform for next‐generation neuromuscular interfaces, continuous health monitoring, and human‐machine interaction.
Fu et al. (Fri,) studied this question.