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January 25, 20260 citationsOpen Access

Towards Comprehensive Benchmarking of Medical Vision Language Models

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DKDimple KhatriSGSanjan TP Gupta

Key Points

  • This research aims to create a reproducible evaluation framework for medical vision-language models in radiology.
  • Developed a benchmarking framework based on the IU-CXR dataset.
  • Integrated various metrics including ROUGE, F1-score, and AUROC for assessment.
  • Conducted ablation studies on model architectures and fine-tuning methods.
  • Analyzed efficiency, latency, and resource usage alongside trust dimensions.
  • Established reproducible baselines for radiology AI models.
  • Demonstrated effectiveness of smaller models in classification and report generation.
  • Identified valuable trade-offs between accuracy, efficiency, and model stability.

Abstract

Medical imaging workflows integrate radiology images with their corresponding free-text reports. Large language models (LLMs) and large vision–language models (LVLMs) achieve strong results but face deployment barriers in hospitals due to computational demands, privacy risks and infrastructure needs. Small language models (SLMs) and small vision–language models (SVLMs), typically under 10 billion parameters, provide a more efficient and auditable alternative for on-premise, privacy-preserving applications in radiology. Recent advancements, including CheXzero, MedCLIP, XrayGPT, LLaVA-Med, MedFILIP and MedBridge, show that smaller multimodal models support classification, retrieval and report generation. Complementary baselines from lightweight SLMs such as DistilBERT, TinyBERT, BioClinicalBERT and T5-Small highlight opportunities for radiology report understanding.Building on these efforts, we propose a reproducible evaluation framework anchored on IU-CXR (for Indiana University Chest X-ray dataset), with potential extensions to CT, MRI and ophthalmology datasets. Our framework integrates task metrics such as ROUGE, F1-score and AUROC, together with efficiency measures including VRAM usage, latency, and model size; alongside trust dimensions like factuality, bias, and robustness. We also conduct ablation studies on model architecture, tokenizers and parameter-efficient fine-tuning (e.g. qLoRA), while analyzing trade-offs between accuracy, efficiency, and stability. This work establishes reproducible baselines and guidance for deploying radiology AI, while also advancing open-source research (available at https://github.com/dimplek0424/MedVLMBenchPhase1).

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Cite This Study

Khatri et al. (2025) studied this question.

synapsesocial.com/papers/6975b4fd5a65d392b01e5d35https://doi.org/10.13016/m2s6gm-0kh6
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