What question did this study set out to answer?

This research aims to identify potential biomarkers related to bipolar disorder and their relevance during the euthymic period.

February 2, 2026Open Access

Neuroserpin, Tissue Plasminogen Activator, Brain-Derived Neurotrophic Factor and Interleukin-6 Serum Levels in Patients with Bipolar Disorder.

Key Points

This research aims to identify potential biomarkers related to bipolar disorder and their relevance during the euthymic period.
Measured serum levels of neuroserpin, tPA, BDNF, and IL-6 in patients with bipolar disorder type 1.
Assessed the relationship between these biomarkers and the euthymic state.
tPA and neuroserpin levels may serve as biomarkers for the euthymic period of bipolar disorder.
Findings provide insights into the underlying mechanisms of bipolar disorder.

Abstract

These findings suggest that tPA and NSP may serve as potential biomarkers for the euthymic period of BD type 1. These biomarkers may provide guidance in understanding the pathophysiology of bipolar disorder.

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