Patients aged ≥65 years with lower gastrointestinal bleeding had a 30-day mortality rate of 7.0% versus 0% in younger patients (p=0.02), with no mortality difference by medication use.
Retrospective Cohort (n=181)
No
Does advanced age and the use of antiplatelet or anticoagulant medications worsen clinical outcomes in patients with lower gastrointestinal bleeding?
While geriatric patients with lower gastrointestinal bleeding have higher mortality and transfusion requirements, the baseline use of antithrombotic medications does not significantly worsen their clinical outcomes.
Absolute Event Rate: 7% vs 0%
p-value: p=0.02
Lower gastrointestinal bleeding has more adverse outcomes in geriatric people. Although anticoagulant and antiplatelet medications increase the risk of bleeding, they have not significantly influenced the clinical outcomes associated with it.
Önem et al. (Fri,) conducted a retrospective cohort in Adults aged ≥18 years admitted to emergency department with symptoms and signs of lower gastrointestinal bleeding undergoing colonoscopy, including a subgroup of geriatric patients aged ≥65 years (n=181). Comparison of patients aged ≥65 to <65 and evaluation of effects of antiplatelet and anticoagulant medication use vs. Patients aged <65 years and geriatric medication subgroups without drug use was evaluated on 30-day mortality (p=0.02). Patients aged ≥65 years with lower gastrointestinal bleeding had a 30-day mortality rate of 7.0% versus 0% in younger patients (p=0.02), with no mortality difference by medication use.
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