What question did this study set out to answer?

The study aims to investigate the effects of arsenic-based homeopathic preparations on glioblastoma multiforme (GBM) cells, focusing on metabolic disruption and cell death mechanisms.

February 11, 2026Asian Pacific Journal of Cancer Prevention0 citationsOpen Access

Arsenic-Based Homeopathic Preparations Induce Metabolic Disruption and Reactive Oxygen Species-Mediated Cell Death in Glioblastoma Multiforme

APAnkit Pateriya CKChirag KulkarniCentral Drug Research Institute MTManendra Singh TomarKing George's Medical University

Key Points

The study aims to investigate the effects of arsenic-based homeopathic preparations on glioblastoma multiforme (GBM) cells, focusing on metabolic disruption and cell death mechanisms.
Laboratory tests on GBM cell lines using arsenicum iodatum and arsenicum album.
Assessment of cell growth inhibition and metabolic changes.
Analysis of reactive oxygen species (ROS) levels and cell death pathways.
Arsenicum iodatum and arsenicum album significantly inhibit the growth of GBM cells.
Cell death is linked to metabolic disruption and increased levels of reactive oxygen species.

Abstract

Arsenicum iodatum and Arsenicum album exhibit growth-inhibitory effects on GBM cells, likely through metabolic disruption and ROS-mediated cell death. Further studies are warranted to elucidate the precise mechanisms of cell death and to evaluate their efficacy and safety in vivo.

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