Deoxygenative Phosphonation of Ketones by Titanium

Key Points

• The research investigates the deoxygenative phosphonation of ketones using a titanium complex.
• Utilized a di-oxo-titanium trichloride complex for reactions.
• Explored the C(sp³)–P coupling process.
• Applied synthetic techniques to generate tertiary phosphine oxides.
• Demonstrated effective phosphonation of ketones using titanium.
• Showed the accessibility of the titanium complex in reactions.
• Revealed potential for broader applications in synthetic chemistry.