What question did this study set out to answer?

To develop an effective drug delivery device for calcium channel blockers using MOF UiO-66.

February 12, 2026Open Access

A rational development of a drug delivery device based on MOF UiO-66 for calcium channel blockers drugs

Key Points

To develop an effective drug delivery device for calcium channel blockers using MOF UiO-66.
Utilized metal-organic framework (MOF) UiO-66 for drug encapsulation.
Evaluated the solubility and absorption properties of Amlodipine, Nifedipine, and Nimodipine.
Analyzed the delivery device's performance in releasing drugs effectively.
Demonstrated enhanced solubility of calcium channel blockers.
Showed improved absorption rates compared to traditional methods.
Suggests potential for better therapeutic outcomes in cardiovascular conditions.

Abstract

The administration of drugs with low solubility or absorption, such as calcium channel blockers (CCB) Amlodipine, Nifedipine, and Nimodipine, affects the recovery of complicated health conditions related to cardiovascular diseases....

Bookmark

View Full Paper

Bookmark

View Full Paper

A rational development of a drug delivery device based on MOF UiO-66 for calcium channel blockers drugs

Key Points

Abstract

Cite This Study