Efficacy and safety of high-definition transcranial direct current stimulation combined with digital rehabilitation on upper limb function in stroke patients: study protocol for a randomized, double-blind, sham-controlled confirmatory trial | Synapse
February 13, 2026Open Access
Efficacy and safety of high-definition transcranial direct current stimulation combined with digital rehabilitation on upper limb function in stroke patients: study protocol for a randomized, double-blind, sham-controlled confirmatory trial
Key Points
The central aim is to assess the efficacy and safety of high-definition transcranial direct current stimulation in improving upper limb function after stroke.
Conduct a randomized, double-blind, sham-controlled trial
Participants include stroke patients
Intervention combines stimulation with digital rehabilitation
Outcomes focus on upper limb functionality
Expected improvements in upper limb function
Safety profile monitored throughout the trial
Abstract
This trial has been registered at the Clinical Research Information Service (Registration number: KCT0010556). Registration date: May 28, 2025.