What question did this study set out to answer?

To investigate the effect of percutaneous vertebroplasty on adjacent intervertebral bridging ossification in patients with thoracolumbar osteoporotic vertebral compression fractures.

February 13, 2026Open Access

Percutaneous Vertebroplasty Reduced the Adjacent Intervertebral Bridging Ossification Rates in Patients With Thoracolumbar Osteoporotic Vertebral Compression Fractures: A Retrospectively Comparison Study

HCHao CaiXinHua Hospital HZHuo‐Liang ZhengXinHua Hospital PCPengbo ChenXinHua Hospital

Key Points

To investigate the effect of percutaneous vertebroplasty on adjacent intervertebral bridging ossification in patients with thoracolumbar osteoporotic vertebral compression fractures.
Reviewed clinical data of 183 patients treated from January 2018 to December 2022.
Divided patients into bridging and non-bridging ossification groups based on ossification occurrence.
Analyzed various clinical parameters and their relationship with bridging ossification.
The highest bridging ossification rate was observed at the T12 level (55.7%).
PVP surgery resulted in a significantly reduced rate of adjacent ossification (p < 0.001).
No significant differences in VAS and ODI scores were found at 12 months post-treatment between groups.

Abstract

ABSTRACT Objective Percutaneous vertebroplasty (PVP) is a commonly used minimally invasive procedure in thoracolumbar osteoporotic vertebral compression fractures (OVCFs) patients. At present, there are no relevant studies on the effects of PVP on the occurrence of adjacent intervertebral bridging ossification. Methods We reviewed clinical data of patients with thoracolumbar OVCFs treated in our hospital between January 2018 and December 2022. Patients were divided into bridging ossification and non‐bridging ossification groups according to whether or not intervertebral bridging ossification had occurred. The clinical data collected included whether PVP surgery was performed, age, sex, body mass index, Hounsfield unit value, bone metabolism indexes, endplate fracture types, thoracic kyphosis, thoracolumbar kyphosis, lumbar lordosis, local kyphosis, Gardner angle, Cobb angle, the ratio of posterior border height (PBH) to anterior border height (ABH), and Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) scores. We investigated the differences in these parameters and analyzed their relationship with intervertebral bridging ossification. Results A total of 183 eligible patients were included in the study. The highest rate of intervertebral bridging ossification was observed at T12 level (55.7%). Ninety patients developed adjacent intervertebral bridging ossification (63 patients received conservative treatment and 27 patients underwent PVP surgery). The rate of intervertebral bridging ossification reduced in PVP patients ( p 0.05). Conservatively managed patients who developed intervertebral bridging ossification had significantly better VAS and ODI scores than those who did not ( p < 0.05). Conclusions PVP reduced the adjacent intervertebral bridging ossification rates in thoracolumbar OVCFs patients. This may be related to the improvement in local mechanical stability. Other influencing factors included age, Hounsfield unit value, Gardner angle, local kyphosis, and PBH/ABH.

AI से पूछें

Bookmark

View Full Paper