Extramedullary hematopoiesis in the spleen contributes to natural killer cell development during infection and inflammation

Key Points

• Investigate the role of extramedullary hematopoiesis in the spleen in developing natural killer cells during infection and inflammation.
• Analyze spleen samples in infected and inflamed models
• Examine cellular development pathways
• Evaluate NK cell population changes
• Increased NK cell development observed in the spleen during infection
• Extramedullary hematopoiesis significantly contributes to NK cell maturation
• The process is vital for effective immune response