Overview on Antifungal Efficacy of Ocimum Species: A Review of Traditional Use, Mechanism of Action, and Potential as Alternative Therapeutics

Human skin serves as a physical barrier, but occasionally fungi can infect it. If this happens on the third layer of the skin, the infection gets worse. To treat fungal infections, antifungal creams, liquids, or sprays based on azole derivatives are available; however, these formulations exhibit a range of adverse effects at the application site. Herbal extracts and other essential oils have demonstrated potent antifungal activity in recent years. In Ayurvedic medicine, Tulsi scientifically referred known as Ocimum sanctum Linn., is a common medicinal herb. Many fungal infection treated with it due to its antibacterial qualities. We have included a current summary of the Tulsi plant's anti-infective qualities in this review, with an emphasis on its antibacterial and antifungal activities.1