Systemic Glucocorticoid Use and Risk of Colorectal Cancer, Especially Early-Onset Type: A Nationwide Cohort Study.

Key Points

• To determine the association between systemic glucocorticoid use and the risk of colorectal cancer, focusing on early-onset cases.
• Conducted a nationwide cohort study
• Analyzed systemic glucocorticoid use in the population
• Identified high-risk groups for colorectal cancer
• Evaluated risk-adapted screening needs
• Systemic glucocorticoid use is linked to a higher risk of colorectal cancer
• Particularly significant association observed for early-onset colorectal cancer
• Identification of new high-risk groups for enhanced screening