Abstract PS1-01-16: Effectiveness of post-discharge management program of breast cancer patients based on Smart Cancer Care 2.0 using patient reported outcome, a preliminary analysis of a randomized clinical trial

Abstract Introduction: In Korea, a “Smart Cancer Care” platform that utilizes patient reported outcomes has been developed to manage treatment side effects of cancer patients and resolve various unmet needs. In this study, we applied a cancer patient post-discharge management program based on Smart Cancer Care 2.0 to breast cancer patients and evaluated its effectiveness. Methods: Breast cancer patients receiving various treatments such as surgery, radiation therapy, and chemotherapy were randomly assigned to a group that received a cancer patient post-discharge management program (group A) and a group that did not (group B). The cancer patient post-discharge management program monitored and managed various treatment side effects that cancer patients may experience, and even provided information on cancer rehabilitation and health behavior improvement. After applying the program in group A for 3 months, breast cancer patients in both groups were followed up for up to 6 months to evaluate and compare health-related quality of life, unexpected visits to medical institutions, etc. Results: As of December 2023, a total of 190 breast cancer patients were registered, and 169 breast cancer patients were preliminary analyzed in this study. As a result of comparing health-related quality of life measured by the EORTC QLQ-C30, no difference in average scores between groups A and B was confirmed at 1 month (Group A: 65.4, Group B: 65.2). However, the difference in scores at 3 months was statistically significant (Group A: 73.8 points, Group B: 64.7 points, p-value: 0.017). Furthermore, even at 6 months, the difference in scores was statistically significant (Group A: 75.7 points, Group B: 64.6 points, p-value: 0.027). Conclusions: The cancer patient post-discharge management program based on Smart Cancer Care 2.0 was estimated to be effective in improving the health-related quality of life of breast cancer patients. Citation Format: S. Koh, J. Kwon, Y. Noh, J. Na, J. Kim, C. Kim, D. Kang, J. Seo, M. Ock. Effectiveness of post-discharge management program of breast cancer patients based on Smart Cancer Care 2.0 using patient reported outcome, a preliminary analysis of a randomized clinical trial abstract. In: Proceedings of the San Antonio Breast Cancer Symposium 2025; 2025 Dec 9-12; San Antonio, TX. Philadelphia (PA): AACR; Clin Cancer Res 2026;32(4 Suppl):Abstract nr PS1-01-16.