Background: Partial hydatidiform mole (PHM) is challenging for pathologists to differentiate from other forms of aneuploidy and degenerative changes in miscarriage material on histology alone. Mater Pathology utilises fluorescent in-situ hybridisation (FISH) for chromosomes 13, 18, 21, X and Y on formalin fixed paraffin embedded (FFPE) tissue for diagnosis of triploidy in products of conception (POC) with villous dysmorphism.
Mathur et al. (Sun,) studied this question.