What question did this study set out to answer?

To assess the safety of Custodiol compared to blood cardioplegia for myocardial protection during mitral valve repair.

February 23, 2026Open Access

Safety of Custodiol for Myocardial Protection in Minimally Invasive Mitral Valve Repair: A Japanese Single-Center Retrospective Comparison with Blood Cardioplegia in Conventional Sternotomy Repair

Key Points

To assess the safety of Custodiol compared to blood cardioplegia for myocardial protection during mitral valve repair.
Conducted a retrospective comparison between Custodiol and blood cardioplegia
Focused on minimally invasive mitral valve repair procedures
Analyzed outcomes related to myocardial protection in a single-center setting
Custodiol was shown to provide comparable myocardial protection compared to blood cardioplegia
Safety outcomes were favorable in the minimally invasive group
No significant differences were observed in adverse events between the two groups

Abstract

Purpose: Research regarding Custodiol’s safety in minimally invasive mitral valve repair remains limited in Asian populations. We compared Custodiol in minimally invasive mitral valve repair to repetitive cold blood cardioplegia in open mitral valve repair.

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Cite This Study

Aizawa et al. (Thu,) studied this question.

synapsesocial.com/papers/699bee551c6c6bad5397ffd2 https://doi.org/https://doi.org/10.5761/atcs.oa.25-00208

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