Identification of the HLA-DQB1*06:144N Allele by Next-Generation Sequencing.

Key Points

• To identify the HLA-DQB1*06:144N allele and understand its genetic implications.
• Utilized next-generation sequencing techniques
• Focused on the HLA-DQB1 gene
• Analyzed nucleotide variations
• Identified HLA-DQB1*06:144N allele
• Observed a single nucleotide substitution
• Introduced a premature stop codon in exon 2